Possible involvement of female sex steroid hormones in intracellular signal transduction mediated by cytokines following traumatic brain injury
… Summarily, ovariectomized (OVX) was done by using an intra-abdominal … the role of classical
and non-classical estrogen receptors in different brain cells, especially in microglia after TBI…
and non-classical estrogen receptors in different brain cells, especially in microglia after TBI…
Shaping microglial phenotypes through estrogen receptors: relevance to sex-specific neuroinflammatory responses to brain injury and disease
M Acosta-Martínez - Journal of Pharmacology and Experimental …, 2020 - ASPET
… hormone levels in young and old animals affect ER subtype … Recent studies suggest that
perturbation of the gut … cytokine production play a major role in ER-mediated effects. E 2 -…
perturbation of the gut … cytokine production play a major role in ER-mediated effects. E 2 -…
Evolution of TLR4 role in mediating the hepatoprotective effects of estradiol after traumatic brain injury in male rats
S Amiresmaili, M Khaksari, N Shahrokhi… - Biochemical …, 2020 - Elsevier
… the liver [2] and digestive tract [3]. The systemic production of … possible role of non-classical
and classical estradiol receptors … Briefly, 125 μl of serum was mixed in a test tube with 1.5 ml …
and classical estradiol receptors … Briefly, 125 μl of serum was mixed in a test tube with 1.5 ml …
[HTML][HTML] Traumatic brain injury in women across lifespan
MO Blaya, AP Raval, HM Bramlett - Neurobiology of disease, 2022 - Elsevier
… -induced systemic effects (lung/brain, gut/brain, etc.) remain … by estrogens through estrogen
receptors at acute time points … in the hippocampus, serum, and female reproductive organs of …
receptors at acute time points … in the hippocampus, serum, and female reproductive organs of …
[HTML][HTML] Sex as a biological variable in preclinical modeling of blast-related traumatic brain injury
… articles to explore the role of the two estrogen receptors (ERs), … Serum levels of ACTH
have been shown to decrease 1 … , throughout the gastrointestinal tract, lungs, and brain that …
have been shown to decrease 1 … , throughout the gastrointestinal tract, lungs, and brain that …
Impact of menopause-associated frailty on traumatic brain injury
SB Sinder, SV Sharma, IS Shirvaikar… - Neurochemistry …, 2024 - Elsevier
… of hormonal changes that extend far beyond reproductive … between serum sclerostin levels
and the free estradiol index in … large effects on gastrointestinal (GI) function, the gut-brain axis …
and the free estradiol index in … large effects on gastrointestinal (GI) function, the gut-brain axis …
[HTML][HTML] Estrogen formation and inactivation following TBI: what we know and where we could go
KA Duncan - Frontiers in endocrinology, 2020 - frontiersin.org
… Traumatic brain injury (TBI) is responsible for various … The majority of these effects are through
estrogen receptor (… cytokines is observed anywhere from 2 to 4 h following injury (83). Thus…
estrogen receptor (… cytokines is observed anywhere from 2 to 4 h following injury (83). Thus…
Sex hormone signaling and regulation of immune function
… agonists or antagonists to the estrogen receptor (ER). Ethinyl … reduces inflammation and
colon pathology and increases … in serum vary across the life course between males and …
colon pathology and increases … in serum vary across the life course between males and …
Differential contribution of estrogen receptors to the intestinal therapeutic effects of 17β-estradiol in a murine model of Parkinson's disease
AA Poirier, M Côté, M Bourque, H Jarras… - Brain Research …, 2022 - Elsevier
… for future estrogen-based hormone therapies during early PD. … on the production of the
proinflammatory cytokine IL-1β and observed … and to decipher the role of each ER sub-types. Our …
proinflammatory cytokine IL-1β and observed … and to decipher the role of each ER sub-types. Our …
[HTML][HTML] Role of estrogen receptors in health and disease
P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
… mass by inhibiting pro-osteoclastic cytokines in T cells and … differential effects of ERs in
different gastrointestinal diseases… The decrease in serum estrogen levels weakens the gastric …
different gastrointestinal diseases… The decrease in serum estrogen levels weakens the gastric …